Week 8 might as well be rivalry week in the NFL.
There are four intradivisional games on the 16-game slate, plus the battle of New York when the Giants “host" the Jets.
Let’s dig into the odds for NFL Week 8.
NFL Week 8 Odds & Betting Lines
All NFL betting odds cited below are current as of Monday, Oct. 23, and courtesy of DraftKings Sportsbook.
Tampa Bay Buccaneers @ Buffalo Bills
Thursday, Oct. 26, 8:15 p.m. ET
- Moneyline: Buccaneers (+275) @ Bills (-345)
- Spread: Buccaneers +7.5 (-110) @ Bills -7.5 (-110)
- Over/Under: Over 41.5 (-110) / Under 41.5 (-110)
Both teams are coming off disappointing, last-second losses. Buffalo is shockingly just a game over .500.
Can the Bucs, who have suddenly lost three of four, keep pace in the extremely winnable NFC South?
New York Jets @ New York Giants
Sunday, Oct. 29, 1 p.m. ET
- Moneyline: Jets (-162) @ Giants (+136)
- Spread: Jets -3 (-112) @ Giants +3 (-108)
- Over/Under: Over 35.5 (-110) / Under 35.5 (-110)
The Giants defense has looked dominant the past two weeks, including limiting the Washington offense to just 273 yards in their 14-7 upset win Sunday.
The Jets defense has been dominant all season. The first to 17 will probably win.
Los Angeles Rams @ Dallas Cowboys
Sunday, Oct. 29, 1 p.m. ET
- Moneyline: Rams (+190) @ Cowboys (-230)
- Spread: Rams +5.5 (-110) @ Cowboys -5.5 (-110)
- Over/Under: Over 45 (-110) / Under 45 (-110)
Dallas will play its first game at JerryWorld in four weeks after consecutive road games and its Week 7 bye.
The Cowboys are 2-0 at home, with a pair of dominant wins over the Jets and Patriots. The Rams are actually 2-1 on the road this season.
Jacksonville Jaguars @ Pittsburgh Steelers
Sunday, Oct. 29, 1 p.m. ET
- Moneyline: Jaguars (-125) @ Steelers (+105)
- Spread: Jaguars -2 (-110) @ Steelers +2 (-110)
- Over/Under: Over 41 (-110) / Under 41 (-108)
Trevor Lawrence and the Jaguars gutted out a narrow win in New Orleans, improving to 4-0 in games played outside of Duval County.
To boost that mark to 5-0, Jacksonville will need to hold off the suddenly hot Steelers, who find themselves just a half-game out of first place in the AFC North.
Houston Texans @ Carolina Panthers
Sunday, Oct. 29, 1 p.m. ET
- Moneyline: Texans (-148) @ Panthers (+124)
- Spread: Texans -3 (-105) @ Panthers +3 (-115)
- Over/Under: Over 42.5 (-110) / Under 42.5 (-110)
Houston is looming just 1.5 games back of Jacksonville for the AFC South lead.
To keep their playoff hopes alive, the Texans will have to win in Carolina against a Panthers side that has not won since Week 18 of 2022.
New Orleans Saints @ Indianapolis Colts
Sunday, Oct. 29, 1 p.m. ET
- Moneyline: Saints (+102) @ Colts (-122)
- Spread: Saints +1.5 (-110) @ Colts -1.5 (-110)
- Over/Under: Over 42.5 (-112) / Under 42.5 (-108)
Both teams will enter with two straight losses, and the loser will likely sink into the abyss of its conference’s playoff race.
Can New Orleans put up points? Can Indy stop the Saints from doing so?
Atlanta Falcons @ Tennessee Titans
Sunday, Oct. 29, 1 p.m. ET
- Moneyline: Falcons (-118) @ Titans (-102)
- Spread: Falcons -1 (-110) @ Titans +1 (-110)
- Over/Under: Over 36.5 (-110) / Under 36.5 (-110)
The first-place Falcons – yes, you read that right – will need to avoid reading their press clipping to ward off a letdown in Tennessee.
The Titans are 2-0 in games played in Nashville this season.
Philadelphia Eagles @ Washington Commanders
Sunday, Oct. 29, 1 p.m. ET
- Moneyline: Eagles (-285) @ Commanders (+230)
- Spread: Eagles -6.5 (-108) @ Commanders +6.5 (-112)
- Over/Under: Over 45 (-110) / Under 45 (-110)
The Eagles looked dominant on both sides of the ball in their 14-point win over the Dolphins on Sunday night.
They’ll head down I-95 to FedEx Field, where they haven’t lost since 2020.
Minnesota Vikings @ Green Bay Packers
Sunday, Oct. 29, 1 p.m. ET
- Moneyline: Vikings (-102) @ Packers (-118)
- Spread: Vikings +1 (-112) @ Packers -1 (-108)
- Over/Under: Over 43.5 (-110) / Under 43.5 (-110)
Green Bay has dropped three straight and is just a half-game out of last place in the NFC North.
Despite their sub-.500 record, the Vikings have a 2-1 record in road games this season.
New England Patriots @ Miami Dolphins
Sunday, Oct. 29, 1 p.m. ET
- Moneyline: Patriots (+380) @ Dolphins (-500)
- Spread: Patriots +10 (-108) @ Dolphins -10 (-112)
- Over/Under: Over 47 (-108) / Under 47 (-112)
Miami has rolled against sub-.500 teams, especially at home, where it is 3-0 and outscored opponents 143-57.
The Pats stopped their three-game losing streak with a surprising win over the Bills, and they played a tight game against the Dolphins in their first game in Week 2.
Cleveland Browns @ Seattle Seahawks
Sunday, Oct. 29, 4:05 p.m. ET
- Moneyline: Browns (+124) @ Seahawks (-148)
- Spread: Browns +2.5 (-110) @ Seahawks -2.5 (-110)
- Over/Under: Over 40.5 (-110) / Under 40.5 (-110)
The Browns have won two straight, despite playing without Deshaun Watson for large stretches.
Meanwhile, Seattle is hanging tough in the NFC West. This could be a sneaky-good game.
Kansas City Chiefs @ Denver Broncos
Sunday, Oct. 29, 4:25 p.m. ET
- Moneyline: Chiefs (-360) @ Broncos (+285)
- Spread: Chiefs -8 (-110) @ Broncos +8 (-110)
- Over/Under: Over 46.5 (-110) / Under 46.5 (-110)
The Broncos finally won a home game under Sean Payton, stunning the Packers on Sunday.
But they’ll have to contend with the big, bad Chiefs, who have won six straight, including a 19-8 win over Denver in Week 6.
Baltimore Ravens @ Arizona Cardinals
Sunday, Oct. 29, 4:25 p.m. ET
- Moneyline: Ravens (-360) @ Cardinals (+285)
- Spread: Ravens -8 (-110) @ Cardinals +8 (-110)
- Over/Under: Over 43.5 (-110) / Under 43.5 (-110)
Baltimore rolled the Lions in a potential Super Bowl preview Sunday.
The Cardinals have lost four straight but have been scrappy at home, where they are 1-2 with a minus-5 point differential.
Cincinnati Bengals @ San Francisco 49ers
Sunday, Oct. 29, 4:25 p.m. ET
- Moneyline: Bengals (+195) @ 49ers (-238)
- Spread: Bengals +5.5 (-110) @ 49ers -5.5 (-110)
- Over/Under: Over 45.5 (-110) / Under 45.5 (-110)
Cincinnati is coming off a bye and has won two straight, but it will have its work cut out against the 49ers and their dominant defense.
Chicago Bears @ Los Angeles Chargers
Sunday, Oct. 29, 8:20 p.m. ET
- Moneyline: Bears (+295) @ Chargers (-375)
- Spread: Bears +8 (-108) @ Chargers -8 (-112)
- Over/Under: Over 45.5 (-112) / Under 45.5 (-108)
The Bears picked up their second win of the season with rookie quarterback Tyson Bagent, but they will have a much more difficult challenge against the Chargers.
L.A. has dropped two straight, to the Cowboys and Chiefs, but has been extremely competitive in both games.
Las Vegas Raiders @ Detroit Lions
Monday, Oct. 30, 8:15 p.m. ET
- Moneyline: Raiders (+285) @ Lions (-360)
- Spread: Raiders +8 (-110) @ Lions -8 (-110)
- Over/Under: Over 44.5 (-110) / Under 44.5 (-110)
The Lions are angry coming off a 38-6 loss to the Ravens.
The Raiders were embarrassed by the Bears in Chicago and may be in for a long night in the Motor City.
NFL Week 8 Betting Trends
Here are some Week 8 betting trends to consider from the 2022 season:
- Favorites finished the week 9-5 straight up (1 pick’em).
- Home teams were 8-7 straight up and 6-9 against the spread.
- Home favorites were 4-5 ATS, while home underdogs went 2-3 (1 pick’em).
- Overs and Unders split the week, going 7-7-1.