NFL Parlays Week 6

Jovan Alford
Last Updated: Oct 14, 2023

Week 5 wasn’t the best for my parlay picks column. However, I did win a same game parlay for the third time in the past four weeks, as the Giants scored less than 18.5 points and the Dolphins covered the 6.5-point first-half spread.

Our best parlay almost came to fruition (HOU ML + NO-NE Under 40.5), but the Texans lost on a game-winning field goal by Falcons kicker Younghoe Koo.

Thankfully, I didn’t go 0-3 for Week 5, but it would be nice to get a clean sweep. Let’s dive into my NFL Week 6 parlays.

NFL Week 6 Parlay Picks

All NFL betting odds used for these Week 6 parlays are current as of Wednesday, Oct. 11, and courtesy of DraftKings Sportsbook.

Best Parlay: SF ML + NE-LV Under 41.5 (+168)

Longshot Parlay: BAL ML + SEA +3 + LAR Over 27.5 Points + BUF 1H +8.5 (+927)

Same Game Parlay: JAX Over 24.5 Points + JAX ML (+116)

NFL Week 6 Best Parlay Bet

Week 6 Best Parlay (+168)

  • 49ers ML (-245) vs Browns
  • Patriots vs Raiders Under 41.5 (-110)

The 49ers have been one of the best teams in the NFL this season, scoring 30 or more points in five straight games en route to a 5-0 record. I don’t see San Francisco slipping up on the road against the Browns this week, who have a solid defense but leave a lot to be desired on offense.

Cleveland QB Deshaun Watson is dealing with a bruised rotator cuff in his right shoulder, which forced him to miss their Week 4 contest against the Ravens. If he can’t play this week, we could see veteran quarterback P.J. Walker, who will have to face a physical defense that made Dak Prescott look pedestrian.

For the second consecutive week, I’ll take the full game Under involving the Patriots as they go on the road to play the Raiders. Mac Jones and New England’s offense has looked out of sync, scoring three points in the last two games.

I know the Raiders’ defense hasn’t been the best (22.8 ppg allowed) this season, but the Pats haven’t shown us anything to believe they will improve. The Under is 4-1 for both teams through five games.

NFL Week 6 Longshot Parlay Bet

Week 6 Longshot Parlay (+927)

  • Ravens ML (-192) vs Titans
  • Seahawks +3 (-112) vs Bengals
  • Rams: Over 27.5 Points (-115) vs Cardinals
  • Bills 1H -8.5 (-110) vs Giants

Baltimore has the weapons at wide receiver to give this Titans’ pass defense issues, which has allowed 240.2 yards per allowed (10th-most in the NFL). The two keys to victory for the Ravens will be to protect Lamar Jackson and slow down star RB Derrick Henry, who has had just one 100-yard rushing performance this season.

If Baltimore defeats Tennessee in London, I also like Seattle to cover the spread on the road against Cincinnati. The Bengals had a solid bounce-back win over the Cardinals without Tee Higgins, but it remains to be seen if they can have good back-to-back outings.

Seattle has played well on the road this season (2-0 against the spread) and can run the ball too (108 yards per game), which the Bengals’ defense (154 yards per game allowed) has struggled with.

  • Check out our top moneyline, ATS, and Over/Under plays in our NFL Week 6 picks.

Lastly, I’m taking the Over on the Rams’ team total and the Bills’ first-half spread against the Giants on Sunday Night Football.

Los Angeles will face a Cardinals squad that has allowed 30 or more points three times this season. Meanwhile, the Bills are 4-1 ATS in the first half, and the Giants are a disappointing 1-4 ATS in the opening half.

NFL Week 6 Same Game Parlay Bet

Colts vs Jaguars Same Game Parlay (+116)

  • Jaguars: Over 24.5 Points (-108)
  • JAX ML (-198) vs Colts

The Jaguars return home after spending the last two weeks in London, where they picked up wins over the Bills and Falcons. Jacksonville has scored 24 points per game over that span, which is a good sign heading into this weekend.

When these teams played each other in Week 1 at Lucas Oil Stadium, the Jaguars dropped 31 points. However, Indianapolis’ defense has only allowed 21 points per game since Week 1.

Nevertheless, if the Jaguars can build off what they did against the Bills, they should hit the Over on the team total and sweep the season series.


Jovan Alford

Jovan Alford is currently a freelance writer at The Game Day. Before TGD, Jovan was a content producer at The Sporting News, focusing on betting and fantasy sports. He also worked at DraftKings Nation and was previously a sports editor at the Philadelphia Metro. Jovan loves betting on player props and playing daily fantasy sports.

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