NFL Week 2 Odds

John Arlia
@johnarlia
Last Updated: Sep 11, 2023

The NFL Week 2 schedule looks rather appetizing from a fan perspective.

This week’s 16-game slate features six divisional matchups, a pair of AFC postseason rematches, another Dallas vs New York showdown, and a Monday Night Football double-header.

With plenty to look forward to, here are the current Week 2 betting odds and lines for the 2023 NFL season.

NFL Week 2 Odds & Betting Lines

All NFL betting odds cited below are current as of Monday, Sept. 11, and courtesy of DraftKings Sportsbook.

Minnesota Vikings @ Philadelphia Eagles

Thursday, Sept. 14, 8:15 p.m. ET

  • Moneyline: Vikings (+280) @ Eagles (-355)
  • Spread: Vikings +7.5 (-108) @ Eagles -7.5 (-112)
  • Over/Under: Over 48.5 (-110) / Under 48.5 (-110)

Las Vegas Raiders @ Buffalo Bills

Sunday, Sept. 17, 1 p.m. ET

  • Moneyline: Raiders (+350) @ Bills (-455)
  • Spread: Raiders +9.5 (-108) @ Bills -9.5 (-112)
  • Over/Under: Over 48 (-110) / Under 48 (-110)

Los Angeles Chargers @ Tennessee Titans

Sunday, Sept. 17, 1 p.m. ET

  • Moneyline: Chargers (-148) @ Titans (+124)
  • Spread: Chargers -3 (-108) @ Titans +3 (-112)
  • Over/Under: Over 45.5 (-108) / Under 45.5 (-112)

Seattle Seahawks @ Detroit Lions

Sunday, Sept. 17, 1 p.m. ET

  • Moneyline: Seahawks (+190) @ Lions (-230)
  • Spread: Seahawks +5.5 (-110) @ Lions -5.5 (-110)
  • Over/Under: Over 50.5 (-110) / Under 50.5 (-110)

Baltimore Ravens @ Cincinnati Bengals

Sunday, Sept. 17, 1 p.m. ET

  • Moneyline: Ravens (+130) @ Bengals (-155)
  • Spread: Ravens +3 (-110) @ Bengals -3 (-110)
  • Over/Under: Over 45.5 (-110) / Under 45.5 (-110)

Chicago Bears @ Tampa Bay Buccaneers

Sunday, Sept. 17, 1 p.m. ET

  • Moneyline: Bears (+124) @ Buccaneers (-148)
  • Spread: Bears +3 (-112) @ Buccaneers -3 (-108)
  • Over/Under: Over 43.5 (-110) / Under 43.5 (-110)

Green Bay Packers @ Atlanta Falcons

Sunday, Sept. 17, 1 p.m. ET

  • Moneyline: Packers (-115) @ Falcons (-105)
  • Spread: Packers -1 (-108) @ Falcons +1 (-112)
  • Over/Under: Over 41.5 (-110) / Under 41.5 (-110)

Indianapolis Colts @ Houston Texans

Sunday, Sept. 17, 1 p.m. ET

  • Moneyline: Colts (-105) @ Texans (-115)
  • Spread: Colts +1 (-110) @ Texans -1 (-110)
  • Over/Under: Over 40 (-110) / Under 40 (-110)

Kansas City Chiefs @ Jacksonville Jaguars

Sunday, Sept. 17, 1 p.m. ET

  • Moneyline: Chiefs (-142) @ Jaguars (+120)
  • Spread: Chiefs -2.5 (-118) @ Jaguars +2.5 (-102)
  • Over/Under: Over 51 (-110) / Under 51 (-110)

New York Giants @ Arizona Cardinals

Sunday, Sept. 17, 4:05 p.m. ET

  • Moneyline: Giants (-205) @ Cardinals (+170)
  • Spread: Giants -4.5 (-110) @ Cardinals +4.5 (-110)
  • Over/Under: Over 38.5 (-110) / Under 38.5 (-110)

San Francisco 49ers @ Los Angeles Rams

Sunday, Sept. 17, 4:05 p.m. ET

  • Moneyline: 49ers (-290) @ Rams (+235)
  • Spread: 49ers -7 (-105) @ Rams +7 (-115)
  • Over/Under: Over 42.5 (-110) / Under 42.5 (-110)

New York Jets @ Dallas Cowboys

Sunday, Sept. 17, 4:25 p.m. ET

  • Moneyline: Jets (+136) @ Cowboys (-162)
  • Spread: Jets +3 (-105) @ Cowboys -3 (-115)
  • Over/Under: Over 46 (-110) / Under 46 (-110)

Washington Commanders @ Denver Broncos

Sunday, Sept. 17, 4:25 p.m. ET

  • Moneyline: Commanders (+145) @ Broncos (-175)
  • Spread: Commanders +3.5 (-112) @ Broncos -3.5 (-108)
  • Over/Under: Over 40 (-110) / Under 40 (-110)

Miami Dolphins @ New England Patriots

Sunday, Sept. 17, 8:20 p.m. ET

  • Moneyline: Dolphins (-135) @ Patriots (+110)
  • Spread: Dolphins -2.5 (-110) @ Patriots +2.5 (-110)
  • Over/Under: Over 46 (-112) / Under 46 (-108)

New Orleans Saints @ Carolina Panthers

Monday, Sept. 18, 7:15 p.m. ET

  • Moneyline: Saints (-155) @ Panthers (+130)
  • Spread: Saints -3 (-110) @ Panthers +3 (-110)
  • Over/Under: Over 40.5 (-110) / Under 40.5 (-110)

Cleveland Browns @ Pittsburgh Steelers

Monday, Sept. 18, 8:15 p.m. ET

  • Moneyline: Browns (-115) @ Steelers (-105)
  • Spread: Browns -1.5 (-108) @ Steelers +1.5 (-112)
  • Over/Under: Over 42 (-110) / Under 42 (-110)

NFL Week 2 Betting Trends

NFL Week 2 is a complicated slate to bet since it’s hard to know how much stock to put into the results from Week 1. Are surprise teams really as good as they were in the opener? Or will they come crashing back to earth?

To get a better sense of how to attack the slate, here are some general Week 2 betting trends from the 2022 season:

  • Favorites were 9-6 straight up (1 pk).
  • Home teams were 11-5 straight up but 8-7-1 against the spread.
  • Home favorites were 4-6 ATS, while home underdogs went 3-1-1.
  • Unders ruled the week, going 10-4-2.

Author

John Arlia

Before joining The Game Day, John served as the National Writer for the United Soccer League, where he primarily covered the USL Championship out of the league’s headquarters in Tampa, FL. A devout soccer fan, John attended the men’s World Cups in Brazil and Russia and can’t wait for the 2026 edition to come to North America. Having also written for Sporting News Canada since getting his master’s from the Walter Cronkite School of Journalism at ASU, John has acquired a diverse sporting background, but considers football, golf, and soccer his three strong suits.

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