Week 12 of the 2023 NFL season is football’s time to shine.
With the country shutting down for the Thanksgiving holiday, the NFL will take center stage with three games on Turkey Day. For the first time ever, the league is also airing a game on Black Friday, meaning pro football will be on four out of five days this upcoming weekend.
With a feast of games, there’ll be ample opportunities for bettors.
Here’s a look at the Week 12 NFL odds.
NFL Week 12 Odds & Betting Lines
All NFL betting odds cited below are current as of Monday, Nov. 20, and courtesy of DraftKings Sportsbook.
Green Bay Packers @ Detroit Lions
Thursday, Nov. 23, 12:30 p.m. ET
- Moneyline: Packers (+295) @ Lions (-375)
- Spread: Packers +7.5 (-110) @ Lions -7.5 (-110)
- Over/Under: Over 46 (-110) / Under 46 (-110)
The Lions are 4-1 at home and remain within striking distance of the NFC’s No. 1 seed. Green Bay has won two of three and still has an outside chance of a wild-card spot.
Washington Commanders @ Dallas Cowboys
Thursday, Nov. 23, 4:30 p.m. ET
- Moneyline: Commanders (+440) @ Cowboys (-600)
- Spread: Commanders +11 (-110) @ Cowboys -11 (-110)
- Over/Under: Over 47.5 (-110) / Under 47.5 (-110)
The Cowboys average 40 points per game and have an average margin of victory of 27.5 points at AT&T Stadium this season.
- Get an in-depth look at our NFL Thanksgiving betting odds.
Washington has dropped seven of its past nine games, including its 31-19 loss to the hapless New York Giants on Sunday.
San Francisco 49ers @ Seattle Seahawks
Thursday, Nov. 23, 8:20 p.m. ET
- Moneyline: 49ers (-310) @ Seahawks (+250)
- Spread: 49ers -7 (-110) @ Seahawks +7 (-110)
- Over/Under: Over 42.5 (-110) / Under 42.5 (-110)
The 49ers once again look like the class of the NFC after their 27-14 win over the Buccaneers.
The Seahawks fell 17-16 to the Rams and may not have quarterback Geno Smith (tricep) for this Thanksgiving night affair.
Miami Dolphins @ New York Jets
Friday, Nov. 24, 3 p.m. ET
- Moneyline: Dolphins (-355) @ Jets (+280)
- Spread: Dolphins -7.5 (-110) @ Jets +7.5 (-110)
- Over/Under: Over 41 (-110) / Under 41 (-110)
The first Black Friday game in NFL history looks lopsided on paper, especially after the Jets’ 32-6 loss in Buffalo where they finally benched Zach Wilson.
The Dolphins have dropped three straight games played outside of Miami but will surely be looking for style points.
New England Patriots @ New York Giants
Sunday, Nov. 26, 1 p.m. ET
- Moneyline: Patriots (-180) @ Giants (+150)
- Spread: Patriots -3.5 (-110) @ Giants +3.5 (-110)
- Over/Under: Over 34 (-110) / Under 45 (-110)
The Giants matched their season high with 31 points in Washington on Sunday, capping a season sweep with a 12-point win.
They’ll seek their second straight victory against New England, which has dropped three straight but is coming off a bye.
Jacksonville Jaguars @ Houston Texans
Sunday, Nov. 26, 1 p.m. ET
- Moneyline: Jaguars (-115) @ Texans (-105)
- Spread: Jaguars -1 (-110) @ Texans +1 (-110)
- Over/Under: Over 47 (-110) / Under 47 (-110)
The winner of this matchup will claim first place in the AFC South.
Houston has won three straight, led by MVP dark horse C.J. Stroud. Jacksonville has won six of seven, including its 34-14 rout of the Titans on Sunday.
Tampa Bay Buccaneers @ Indianapolis Colts
Sunday, Nov. 26, 1 p.m. ET
- Moneyline: Buccaneers (+105) @ Colts (-125)
- Spread: Buccaneers +1.5 (-110) @ Colts -1.5 (-110)
- Over/Under: Over 42.5 (-110) / Under 42.5 (-110)
The Bucs have dropped five of six but are still somehow only a game out of first place in the NFC South.
The Colts have won two straight and are within a game of the final AFC playoff spot.
Pittsburgh Steelers @ Cincinnati Bengals
Sunday, Nov. 26, 1 p.m. ET
- Moneyline: Steelers (-112) @ Bengals (-108)
- Spread: Steelers -1 (-105) @ Bengals +1 (-115)
- Over/Under: Over 35 (-110) / Under 35 (-110)
The Steelers’ two-game win streak was snapped by the Browns on Sunday.
They’ll face the Bengals, who are reeling with the news that quarterback Joe Burrow (wrist) will miss the rest of the season.
New Orleans Saints @ Atlanta Falcons
Sunday, Nov. 26, 1 p.m. ET
- Moneyline: Saints (-108) @ Falcons (-112)
- Spread: Saints +1 (-115) @ Falcons -1 (-105)
- Over/Under: Over 42.5 (-110) / Under 42.5 (-110)
Both teams are coming off their bye in a game with huge playoff implications.
Atlanta has dropped three straight games, most recently falling 25-23 to the Cardinals in Week 10, but is still within a game of the Saints for first place in the NFC South.
Carolina Panthers @ Tennessee Titans
Sunday, Nov. 26, 1 p.m. ET
- Moneyline: Panthers (+154) @ Titans (-185)
- Spread: Panthers +4 (-110) @ Titans -4 (-110)
- Over/Under: Over 37 (-110) / Under 37 (-110)
The Titans haven’t lost at Nissan Stadium this season but have dropped three straight and five of six. Carolina is 0-5 on the road with an average margin of defeat of 13.2 points per game.
Cleveland Browns @ Denver Broncos
Sunday, Nov. 26, 4:05 p.m. ET
- Moneyline: Browns (+105) @ Broncos (-125)
- Spread: Browns +1.5 (-110) @ Broncos -1.5 (-110)
- Over/Under: Over 36.5 (-110) / Under 36.5 (-110)
The Browns have won five of six, including their 13-10 victory over the Steelers on Sunday. Meanwhile, four straight wins have brought the Broncos back from the dead after a 1-5 start.
Los Angeles Rams @ Arizona Cardinals
Sunday, Nov. 26, 4:05 p.m. ET
- Moneyline: Rams (-112) @ Cardinals (-108)
- Spread: Rams -1 (-105) @ Cardinals +1 (-110)
- Over/Under: Over 44.5 (-110) / Under 44.5 (-110)
Arizona battled but fell to the Texans by five points on Sunday. On the bright side, the Cardinals are 2-0 against the spread since Kyler Murray’s return from injury.
The Rams, who defeated Arizona 26-9 in Week 6, snapped their three-game losing streak with a 17-16 win over Seattle on Sunday.
Kansas City Chiefs @ Las Vegas Raiders
Sunday, Nov. 26, 4:25 p.m. ET
- Moneyline: Chiefs (-410) @ Raiders (+320)
- Spread: Chiefs -9.5 (-110) @ Raiders +9.5 (-110)
- Over/Under: Over 44 (-110) / Under 44 (-110)
The Raiders are 2-1 under interim coach Antonio Pierce and have covered the spread in each game. They’ll host a Chiefs squad on a short week following their Super Bowl rematch against the Eagles.
Buffalo Bills @ Philadelphia Eagles
Sunday, Nov. 26, 4:25 p.m. ET
- Moneyline: Bills (+142) @ Eagles (-170)
- Spread: Bills +3.5 (-110) @ Eagles -3.5 (-110)
- Over/Under: Over 47.5 (-110) / Under 47.5 (-110)
The Bills pulled their season back from the brink with a 26-point win over the Jets on Sunday. They can claw back into the AFC postseason field with a victory in Philadelphia.
However, the Eagles are 4-0 at home this season, with three one-possession wins at Lincoln Financial Field.
Baltimore Ravens @ Los Angeles Chargers
Sunday, Nov. 26, 8:20 p.m. ET
- Moneyline: Ravens (-185) @ Chargers (+154)
- Spread: Ravens -4 (-110) @ Chargers +4 (-110)
- Over/Under: Over 46 (-110) / Under 46 (-110)
The Ravens are rolling and within striking distance of the AFC’s No. 1 seed.
The Chargers have dropped two straight and will be in play-out-the-string mode if they fall at home to Baltimore.
Chicago Bears @ Minnesota Vikings
Monday, Nov. 27, 8:15 p.m. ET
- Moneyline: Bears (+142) @ Vikings (-170)
- Spread: Bears +3.5 (-118) @ Vikings -3.5 (-102)
- Over/Under: Over 45 (-110) / Under 45 (-110)
The Vikings’ five-game win streak was snapped Sunday night in Denver. They’ll try to avenge that and their 19-13 loss in Chicago on Oct. 15 when they host the Bears on Monday night.
Chicago got quarterback Justin Fields back this past weekend and is 2-0-1 against the spread in its past three games.
NFL Week 12 Betting Trends
Here are some Week 12 betting trends to consider from the 2022 season:
- Favorites finished the week 10-4 straight up (two pick’ems).
- Home teams were just 11-5 straight up and 11-3 against the spread (two pick’ems).
- Home favorites were 7-3 ATS, while home underdogs went 4-0.
- Unders edged out Overs, going 8-7-1 on the week.