Thank you for reading our NFL Monday Night Football odds this season.
We will update this page once the 2024 MNF schedule is released in May.
In the meantime, stay up to date with all the latest NFL odds & betting picks at The Game Day Football.
From year to year, the NFL always makes notable changes to improve its primetime lineup.
In 2023, we will see three Monday Night Football double-headers, giving fans even more football to watch at the end of each week.
Let’s look at the MNF schedule for this season and make some picks on the latest Monday Night Football odds.
NFL Monday Night Football Odds & Lines
NFL odds used for these predictions are current as of Tuesday, Dec. 19, and provided by DraftKings Sportsbook.
Week 1: Buffalo Bills vs New York Jets
Bills -1.5 (-110) @ Jets +1.5 (-110)
The new-look Jets, led by quarterback Aaron Rodgers, will kick off the season against the three-time defending AFC East champion Buffalo Bills.
While Rodgers’ debut in the green and white will be the prevailing storyline, New York’s defense — which held Buffalo to 37 points in two meetings last season — could be the difference in this rivalry game.
Week 2: New Orleans Saints vs Carolina Panthers
Saints -3 (-115) @ Panthers +3 (-105)
The front end of this Monday Night Football double-header will feature two NFC South squads that enter the season with new starting quarterbacks.
The Saints signed veteran signal-caller Derek Carr in free agency, while the Panthers traded up to the No. 1 pick in the 2023 NFL Draft to select Bryce Young.
I would back the experience of Carr under the bright lights, even on the road.
Week 2: Cleveland Browns vs Pittsburgh Steelers
Browns -2 (-110) @ Steelers +2 (-110)
The Steelers have won three of their last four games against Cleveland, including a Week 18 matchup last season that was pivotal in keeping Pittsburgh’s playoff hopes alive.
However, the Browns should be much improved in 2023, with Deshaun Watson having the benefit of a full offseason.
Cleveland will be a team to watch early in the campaign.
Week 3: Philadelphia Eagles vs Tampa Bay Buccaneers
Eagles -4.5 (-110) @ Buccaneers +4.5 (-110)
The Buccaneers are one of the NFL’s surprise teams, starting the season 2-0 under new quarterback Baker Mayfield.
Philadelphia is also 2-0 but posted a 2-5 ATS mark last season as a road favorite. That isn’t exactly convincing, but Jalen Hurts and Co. have extra rest after playing on TNF in Week 2.
The Eagles should win this game, but I’m less confident in their ability to cover this number.
Week 3: Los Angeles Rams vs Cincinnati Bengals
Rams +3 (-110) @ Bengals -3 (-110)
Week 3 wraps up with a rematch of Super Bowl 56, which the Rams won 23-20 at SoFi Stadium.
- Get the latest Super Bowl 58 betting odds.
Los Angeles hasn’t been able to find that level of play since, while the Bengals have been as good as advertised.
However, if Joe Burrow (calf) can’t suit up, the Rams could knock off Cincy once again.
Week 4: Seattle Seahawks vs New York Giants
Seahawks +1.5 (-110) @ Giants -1.5 (-110)
The Seahawks and Giants were the surprises of the 2022 season thanks in large part to impressive quarterback play from Geno Smith and Daniel Jones.
Smith got the better of Jones in their head-to-head matchup last season, throwing for 212 yards and a pair of scores in a 27-13 victory.
New York head coach Brian Daboll will have his group fired up for a shot at revenge, and the Giants have a rest advantage after playing on Thursday night in Week 3.
Week 5: Green Bay Packers vs Las Vegas Raiders
Packers +1.5 (-110) @ Raiders -1.5 (-110)
Davante Adams will face his former team for the first time since being traded to Las Vegas last March.
After racking up over 1,500 yards and 14 touchdowns in his first campaign with the Raiders, Adams should be targeted early and often by new QB Jimmy Garoppolo.
Week 6: Dallas Cowboys vs Los Angeles Chargers
Cowboys -2 (-110) @ Chargers +2 (-110)
Will this be the Kellen Moore revenge game?
The Chargers’ new offensive coordinator was let go by the Cowboys in January after a four-year run, and I’m sure he’ll have some tricks up his sleeves to use against a talented Dallas defense.
This matchup could produce some fireworks between Justin Herbert and Dak Prescott.
Week 7: San Francisco 49ers vs Minnesota Vikings
49ers -7.5 (-110) @ Vikings +7.5 (-110)
The Vikings went 8-1 at home during the 2022 regular season but are 0-3 at U.S. Bank Stadium to start the 2023 campaign.
San Francisco posted a 12-3 mark straight up and against the spread in conference games last season and is the far more balanced team.
After losing their first game last week, the Niners should bounce back against the Justin Jefferson-less Vikes.
Week 8: Las Vegas Raiders vs Detroit Lions
Raiders +8 (-110) @ Lions -8 (-110)
The Lions, preseason favorites in the NFC North odds, have lived up to their lofty expectations after getting off to a 5-2 start.
Jared Goff has continued to play sensational football at Ford Field, throwing for over 800 yards and posting a 7:2 TD:INT ratio in three home contests.
Detroit is tailor-made for a six-point teaser, but laying the points with the hosts isn’t a bad idea, either.
Week 9: Los Angeles Chargers vs New York Jets
Chargers -3 (-110) @ Jets +3 (-110)
This game has significant implications for the AFC playoff picture.
The Chargers have won four straight against New York and saved their season with a victory over the Bears on Sunday night. Meanwhile, the Jets escaped MetLife with an ugly road overtime win over the rival Giants earlier in the afternoon.
This should be another close contest, but Justin Herbert and LA’s offense should make enough plays to get the win.
Week 10: Denver Broncos vs Buffalo Bills
Broncos +7.5 (-110) @ Bills -7.5 (-110)
After acquiring Russell Wilson, the Broncos had a heavy dose of primetime games early last season, which, to put it mildly, were painful to watch. Denver mustered just 52 combined points across four nationally-televised games, two of which went to overtime.
- Get in on the early-week action with our Thursday Night Football odds.
New head coach Sean Payton has turned things around slightly in recent weeks, but the best bet is to take the Bills in a teaser.
Week 11: Philadelphia Eagles vs Kansas City Chiefs
Eagles +3 (-110) @ Chiefs -3 (-110)
Monday Night Football is usually must-see TV, but this Week 11 matchup takes the cake.
Jalen Hurts and the Eagles will get a chance to avenge their Super Bowl 57 defeat to the Chiefs, who won their second Lombardi Trophy in four years thanks to the second-half heroics of Patrick Mahomes.
Given the narrative, I’m tempted to take Philly and the points.
Week 12: Chicago Bears vs Minnesota Vikings
Bears +3.5 (-110) @ Vikings -3.5 (-110)
One week you get a Super Bowl rematch; the next, you get a battle of middling teams in the NFC North. Such is life.
The Vikings have won five straight games in this rivalry, with each victory coming by at least six points.
However, Chicago nearly beat division-leading Detroit in Justin Fields‘ return from injury last week. This game will very likely end on three, so give me the Bears and the points.
Week 13: Cincinnati Bengals vs Jacksonville Jaguars
Bengals +8.5 (-110) @ Jaguars -8.5 (-110)
This matchup delivered plenty of promise when it pitted two of the top young quarterbacks in football (and two former No. 1 overall picks) against each other. However, after Joe Burrow’s season-ending injury, this should be a relative walk in the park for Trevor Lawrence’s Jaguars.
Jacksonville took a big step toward winning the AFC South by beating the Texans on Sunday and will need to continue racking up wins to secure at top-two seed in the AFC playoffs.
Week 14: Tennessee Titans vs Miami Dolphins
Titans +13.5 (-110) @ Dolphins -13.5 (-110)
The final Monday Night Football double-header of the 2023 NFL season will start with what looks like a lopsided AFC showdown.
This spread has moved six points in Miami’s direction since the offseason, which makes sense given their impressive record against sub-.500 teams.
Tennessee head coach Mike Vrabel is one of the league’s top coaches and seems to do his best work as an underdog. However, his team has plenty of injury concerns for a short week.
Week 14: Green Bay Packers vs New York Giants
Packers -6.5 (-110) @ Giants +6.5 (-110)
This game is the second of back-to-back primetime outings for the Packers, who knocked the Chiefs at Lambeau on Sunday Night Football in Week 13.
- Stay on top of the latest Sunday Night Football odds.
Meanwhile, the Giants are coming off a bye. New York has won back-to-back games with Tommy DeVito, but overcoming a peaking Green Bay side could be a step too far.
Week 15: Philadelphia Eagles vs Seattle Seahawks
Eagles -4 (-110) @ Seahawks +4 (-110)
The Chiefs and Patriots were initially scheduled for Monday Night Football in Week 15, but the NFL nicely flexed in what looks to be a more meaningful and competitive matchup.
- Get ready for primetime with our Monday Night Football predictions.
Both these teams desperately need a win to put an end to their current losing runs. Philadelphia has lost back-to-back games and consequentially relinquished hold of the NFC’s No. 1 seed and the NFC East lead.
Meanwhile, Seattle has dropped four straight and is currently outside the NFC playoff picture on tiebreakers. Getting QB Geno Smith (groin) back this week would be huge.
Week 16: Baltimore Ravens vs San Francisco 49ers
Ravens +5.5 (-110) @ 49ers -5.5 (-110)
The 2023 Monday Night Football slate comes to a close on Christmas Day when the Ravens visit the 49ers in the finale of a holiday triple-header.
- Check out the full NFL Christmas Day odds.
Two run-heavy offenses should meet some resistance from two of the league’s top rushing defenses in what will be a physical postseason precursor.
If you’re looking for a last-minute gift, I’d probably take the Under.