49ers Odds 2023

John Arlia
Last Updated: Jun 29, 2023

The San Francisco 49ers had enough talent to win the Super Bowl last season; they simply ran out of quarterbacks.

Week 1 starter Trey Lance broke his ankle in Week 2, Jimmy Garoppolo fractured his foot in Week 13, and Brock Purdy and Josh Johnson were forced out of San Francisco’s NFC Championship Game loss to the Philadelphia Eagles. That’s horrible luck.

Heading into 2023, head coach Kyle Shanahan will stick with Purdy, the final pick of the 2022 NFL Draft who stepped in admirably after the team’s top two options went down.

As we prepare for the upcoming season, let’s examine the latest 49ers betting odds.

49ers Futures Betting Odds

Note: These NFL betting odds are current as of Thursday, June 29, and provided by DraftKings Sportsbook.

  • Win Super Bowl: +1000
  • Win NFC Championship: +425
  • Win NFC West: -160
  • Make Playoffs: Yes (-425) / No (+340)
  • Regular-Season Win Total: Over 10.5 (-145) / Under 10.5 (+125)

49ers Super Bowl 58 Odds

49ers: Win Super Bowl (+1000)

The 49ers have the fourth-best odds to win Super Bowl 58, falling only behind the Chiefs (+600), Eagles (+650), and Bills (+900).

And although the price is short, this is a pretty intriguing bet.

San Francisco is a team that has been trending toward a Lombardi Trophy in recent years, and it’s hard to ignore their talent on both sides of the ball.

The league’s top statistical defense from a season ago only got better this offseason, adding defensive tackle Javon Hargrave to an already fearsome front.

On offense, the midseason addition of Christian McCaffrey gave this unit another multi-dimensional weapon to pair with other top talents in Deebo Samuel, George Kittle, and Brandon Aiyuk.

As long as the 49ers get consistent quarterback play, something that held them back in the Garoppolo era, this team can finally get over the hump.

49ers NFC Championship Odds

49ers: Win NFC Championship (+425)

The 49ers have reached the conference championship game three of the last four years, so I don’t think these NFC Championship odds are appropriately priced.

San Francisco is one of three NFC teams with a Super Bowl-caliber roster and significant playoff experience. Philadelphia and Dallas can also make that claim.

But given the lack of depth at the top of the conference and the likelihood Kyle Shanahan’s squad returns to the title game, this feels like a good bet.

49ers NFC West Winner Odds

49ers: Win NFC West (-160)

Despite a strong history of playoff performance, the 49ers have only won four division titles since 2010. In that span, they’ve made six NFC Championship Game appearances.

That’s pretty staggering.

Then again, the division has long been one of the most competitive in the NFL as San Francisco has contended with talented Seahawks, Rams, and Cardinals teams.

That isn’t the case this season, as the 49ers are comfortable favorites atop the NFC West odds. The only team likely to threaten is Seattle (+195), who San Francisco defeated three times head-to-head last season (including playoffs).

Barring more quarterback injuries, the Niners should cruise to a second straight division title.

49ers Make Playoffs Odds

49ers: Make Playoffs (-425)

The 49ers have -425 odds of making the NFL playoffs in 2023, implying an 81% chance to return to the postseason.

While we’ve seen teams like the Rams fall off significantly after strong seasons, this roster remains stacked.

There isn’t much value in betting on this prop, but it could be helpful as a season-long parlay piece.

49ers Regular-Season Win Total Odds

49ers: Over 10.5 Wins (-145)

After winning 13 games a season ago, San Francisco’s regular-season win total is set at 10.5 games.

That differential explains why the Over (-145) is heavily juiced compared to the Under (+125).

While the Niners face a first-place schedule and are matched up with the NFC East and AFC North, two relatively strong divisions in their own right, this team has too much talent to finish worse than 11-6.


John Arlia

Before joining The Game Day, John served as the National Writer for the United Soccer League, where he primarily covered the USL Championship out of the league’s headquarters in Tampa, FL. A devout soccer fan, John attended the men’s World Cups in Brazil and Russia and can’t wait for the 2026 edition to come to North America. Having also written for Sporting News Canada since getting his master’s from the Walter Cronkite School of Journalism at ASU, John has acquired a diverse sporting background, but considers football, golf, and soccer his three strong suits.

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